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Conclusion: Cigarette smoking was found to be significantly associated with a reduced risk of endometrial cancer, especially among postmenopausal women.
It's probably the nicotine. Everything in moderation.
Maybe this effect is somehow related to the fact that endometrial cancer is lower in women who smoke:
Addicts don't moderate.
Patrick says
Maybe this effect is somehow related to the fact that endometrial cancer is lower in women who smoke:
It’s a conundrum. Likewise, the beneficial effects of obesity.
That's true for every addiction. There are plenty of people who smoke casually or rarely.
Despite all the negatives, research occasionally finds a positive feature of smoking, like reduced gout risk. Gout is a painful type of arthritis that develops when monosodium urate crystals accumulate in your joints, but smokers appear to have a lower risk for this condition.
Association of height, BMI, and smoking status with prostate cancer risk before and after the introduction of PSA testing in Sweden
The association between smoking status (current vs. never) and risk of PCa also changed from null before the PSA era to strong and negative in the PSA era, with evidence of interaction between periods. Several systematic reviews, meta-analyses, and Mendelian randomisation studies provide strong evidence of a negative association between current smoking and PCa risk, especially localised/non-aggressive PCa8,10,11,36. This association is mostly observed in studies conducted during the PSA era10,12,36. Additionally, our previous study using five Swedish cohorts showed that smoking in combination with obesity was associated with a further decrease in risk of non-aggressive PCa12. Similar to men with obesity, smokers are less likely to take an asymptomatic PSA test37, which together with the increased availability of such tests over time, most likely explain our observed time trend of the association between smoking and PCa.
https://www.nature.com/articles/s41598-025-06548-y